EFFECT OF ADDING CHLOROGENIC ACID ON BROILER PERFORMANCE, SOME BLOOD BIOCHEMICAL PARAMETERS AND GUT HEALTH

Authors

DOI:

https://doi.org/10.36103/trrq9j63

Keywords:

acid, chickens, gut histomorphology, blood biochemistry

Abstract

This study was conducted to evaluate the effectiveness of chlorogenic acid on productive performance, blood biochemistry and intestinal histomorphology of broiler chickens. A total of 256-day old Ross 308 broiler chicks were divided into 4 treatments with 4 replications, 16 chicks per replicate. Treatments were arranged as follow: control group was left without any additive, whereas group 2-4 supplemented with 1, 1.5 and 2 mL of chlorogenic acid per litter of drinking water respectively. Results of this study showed that the body weight gain of birds received chlorogenic acid significantly increased when compared to control group. Lowest feed intake (P<0.05) was recorded for the birds received 1.5ml of chlorogenic acid than other experimental groups. Better feed conversion ratio was found in birds offered 1 and 1.5 mL chlorogenic acid compared to the control and those offered 2 mL /L of chlorogenic acid. The chlorogenic acid   significantly increased villous heights and reduced crypt depths. The higher villous surface area was recorded for the birds received 1 mL of chlorogenic acid (P<0.05) than other groups. The birds in control group significantly increased the serum content of globulin over all treatments. It can be concluded that chlorogenic acid had a positive effect on performance and gut health of broiler chickens.

References

Afsharmanesh, M., and J. Pourreza, 2005. Effects of calcium, citric acid, ascorbic acid, vitamin D3 on the efficacy of microbial phytase in broiler starters fed wheat-based diets I. Performance, bone mineralization and ileal digestibility. International Journal of Poultry Science, 4(6), 418-424. https://doi.org/10.3923/ijps.2005.418.424

Chang, R., S. P., F. Jing, Y. Liu, and J. Chen, 2019. A comparative study on biochar properties and Cd adsorption behavior under effects of ageing processes of leaching, acidification and oxidation. Environmental Pollution, 254, 113123. https://doi.org/10.1016/j.envpol.2019.113123

Beski, S. S. M., S. A. M’Sadeq, S. M. Hussein, and A. L. Mahmod. 2021. performance and physiological responses of broiler chickens to dietary combination of yeast and medical plants. Iraqi Journal of Agricultural Sciences, 52(5), 1117-1125. https://doi.org/10.36103/ijas.v52i5.1450

Hadi, K. A., S. D. S. Al-douri, and D. H. Hadree. 2023. Effect of folic acid on some physiological parameters in female rabbits treated with methotrexate. Iraqi Journal of Agricultural Sciences, 54(3), 730-734. https://doi.org/10.36103/ijas.v54i3.1754

Jing, M., Li, Y., J. Zeng, P. Huang, M. Skirzewski, O. Kljakic and J. Zou, 2020. An optimized acetylcholine sensor for monitoring in vivo cholinergic activity. Nature methods, 17(11), 1139-1146. https://doi.org/10.1038/s41592-020-0953-2

Kramer, P. F., S. G. Brill-Weil, A. C. Cummins, R. Zhang, G. A. Camacho-Hernandez, A. H. Newman, and Z. M. Khaliq, 2022. Synaptic-like axo-axonal transmission from striatal cholinergic interneurons onto dopaminergic fibers. Neuron, 110(18), 2949-2960. https://doi.org/10.1016/j.neuron.2022.07.011

Li, X., B. Yu, Q. Sun, Y. Zhang, M. Ren, X. Zhang, and Q. Luo, 2018. Generation of a whole-brain atlas for the cholinergic system and mesoscopic projectome analysis of basal forebrain cholinergic neurons. Proceedings of the National Academy of Sciences, 115(2), 415-420. https://doi.org/10.1073/pnas.1703601115

Liu, H., P. Chen, X. Lv, Y. Zhou, X. Li, S. Ma, and J. Zhao, 2022. Effects of chlorogenic acid on performance, anticoccidial indicators, immunity, antioxidant status, and intestinal barrier function in coccidia-infected broilers. Animals, 12(8): 963.‏ http://dx.doi.org/10.3390/ani12080963

Lu, H., Z. Tian, Y. Cui, Z. Liu, and X. Ma, 2020. Chlorogenic acid: A comprehensive review of the dietary sources, processing effects, bioavailability, beneficial properties, mechanisms of action, and future directions. Comprehensive reviews in food science and food safety, 19(6), 3130-3158. https://doi.org/10.1111/1541-4337.12620

Lückstädt, C. 2008. The use of acidifiers in fish nutrition. CABI Reviews 2008 , pp. 8 http://www.cababstractsplus.org/cabreviews

McCrea, B., Macklin, K., Norton, R., Hess, J., and S. Bilgili, 2005. Recovery of Campylobacter jejuni front broiler house samples during four consecutive flocks: Dendrogram. in poultry science (vol. 84, pp. 15-15). 1111 n dunlap ave, savoy, il 61874-9604 usa: poultry science assoc inc

M'Sadeq, S.A., S. Wu, R. Swick, and M. Choct, 2015. Towards the control of necrotic enteritis in broiler chickens with in-feed antibiotics phasing-out worldwide. Animal Nutrition, 1(1): 1-11. https://doi.org/10.1016/j.aninu.2015.02.004

M'Sadeq, S., R. A. Swick, M. Choct, and S. Wu, 2016. The role of coated sodium butyrate on performance of broilers fed high protein and reduced energy diets. Journal of Applied Animal Nutrition, 4, e2. https://doi:10.1017/jan.2015.13

Mroz, Z. 2005. Organic acids as potential alternatives to antibiotic growth promoters for pigs. Advances in pork production, 16(1), 169-182. https://shorturl.at/bCDK7

Mustafa, A. A., and I. T. Tayeb. 2022. The influence of dietary salvia and lavender powders on productive performance, some physiological parameters, and immunity of broiler under stocking density stress. Iraqi Journal of Agricultural Sciences, 53(6), 1280-1288. https://doi.org/10.36103/ijas.v53i6.1642

Naveed, M., V. Hejazi, M. Abbas, A. A. Kamboh, G. J. Khan, M. Shumzaid, and F. Modarresi-Ghazani, 2018. Chlorogenic acid (CGA): A pharmacological review and call for further research. Biomedicine & Pharmacotherapy, 97, 67-74. https://doi.org/10.1016/j.biopha.2017.10.064

Oberländer, B., K. Failing, C.M. Jüngst, N. Neuhaus, M. Lierz, and F. Möller Palau-Ribes, 2020. Evaluation of Newcastle Disease antibody titers in backyard poultry in Germany with a vaccination interval of twelve weeks. Plos one, 15(8), p.e0238068. https://doi.org/10.1371/journal.pone.0238068

Reisinger, N., T. Steiner, S. Nitsch, G. Schatzmayr, and T.J. Applegate, 2011. Effects of a blend of essential oils on broiler performance and intestinal morphology during coccidial vaccine exposure. Journal of Applied Poultry Research, 20(3), 272-283. https://doi.org/10.3382/japr.2010-00226

Santana-Gálvez, J., L. Cisneros-Zevallos, and D. A. Jacobo-Velázquez, 2017. Chlorogenic acid: Recent advances on its dual role as a food additive and a nutraceutical against metabolic syndrome. Molecules, 22(3): 358. https://doi.org/10.3390/molecules22030358

Smulikowska, S., J. Czerwinski, A. Mieczkowska, and J. Jankowiak, 2009. The effect of fat-coated organic acid salts and a feed enzyme on growth performance, nutrient utilization, microflora activity, and morphology of the small intestine in broiler chickens. Journal of Animal and Feed Sciences, 18(3): 478-489. https://doi.org/10.22358/jafs/66422/2009

Stohl, W., B. Kenol, A.J. Kelly, A.A. Correa, and R.S. Panush, 2019, December. Elevated serum globulin gap as a highly reliable marker of elevated erythrocyte sedimentation rate in patients with systemic rheumatic diseases. In Seminars in Arthritis and Rheumatism 49, (3): 485-492). WB Saunders. https://doi.org/10.1016/j.semarthrit.2019.05.001

Teng, P.Y., S. Yadav, T.S. Dos Santos, A.L. Fuller, and W.K. Kim, 2020. 2-Nitro-1-propanol improved nutrient digestibility and oocyst shedding but not growth performance of Eimeria-challenged broilers. Poultry science, 99, 4314–4322.‏ https://doi.org/10.1016/j.psj.2020.05.038

Xu, Z.R., C.H. Hu, M.S. Xia, X.A. Zhan, and M.Q. Wang, 2003. Effects of dietary fructooligosaccharide on digestive enzyme activities, intestinal microflora and morphology of male broilers. Poultry Science, 82, 1030–1036. https://doi.org/10.1093/ps/82.6.1030

Zhang, K., X. Li, J. Zhao, Y. Wang, X. Hao, K. Liu,and and H. Liu, 2022 Protective effects of chlorogenic acid on the meat quality of oxidatively stressed broilers revealed by integrated metabolomics and antioxidant analysis. Food Funct. 13, 2238–2252. http://dx.doi.org/10.1039/D1FO03622J

Zhang, X., Q. Zhao, X. Ci, S. Chen, Z. Xie, H. Li, H. Zhang, F. Chen, and Q. Xie, (2020). Evaluation of the efficacy of chlorogenic acid in reducing small intestine injury, oxidative stress, and inflammation in chickens challenged with Clostridium perfringens type A. Poulrtry Science, 99, 6606–6618. https://doi.org/10.1016%2Fj.psj.2020.09.082

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2024-04-28

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How to Cite

A. T. M. Khishtan, S. A. M’Sadeq, S. S. M. Beski, & S. M. Ameen Omar. (2024). EFFECT OF ADDING CHLOROGENIC ACID ON BROILER PERFORMANCE, SOME BLOOD BIOCHEMICAL PARAMETERS AND GUT HEALTH. IRAQI JOURNAL OF AGRICULTURAL SCIENCES, 55(2), 652-658. https://doi.org/10.36103/trrq9j63

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